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bremelanotide record
11/10/09 at 03:30:18
 
Just ordered bremelanotide (PT-141) from TanResearch tonight.  ED and SD for the last two years, kept in check with daily cialis and yohimbe/epimedium/l'arginine for sessions.  Newly found ultra-low libido since giving up Yohimbe last week (not interested in anything).  Too much lost sleep for that herb, though good results except heart pounds during strenuous sex, and I need take breaks in middle.  Just remarried the love of my life at 43, and not taking this SD laying down.  My new wife has very healthy attitude and appetite, finally after 20 years of waiting.  Doc says lay off cialis, this probably all in my head, but left with nothing I am becoming depressed.  Just want healthy sex life for a while, don't need to be superman, or at least not every time.
 
Wanting to experiment to get a handle on what is not working - plumbing, wiring, or both.  Hate needles, but trying bremelanotide (PT-141).  Want to also try Cabergoline, if I can find a reliable source, to see if prolactin might be problem.  Anyone have reliable source no script...be appreciated.  I will report my dosage, and results of bremelanotide (PT-141) and any combo.  If anyone has other ideas of a regimen or other meds, herbs, combos, plz do tell.
 
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Re: bremelanotide record
Reply #1 - 11/10/09 at 08:34:28
 
hi, did you use the nasal spray?  
Spray not good. you can buy the injection vial.
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Reply #2 - 11/10/09 at 12:02:07
 
Ordered bremelanotide (PT-141). haven't received yet.  Plan to inject.  Just starting my log.
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Re: bremelanotide record
Reply #3 - 11/10/09 at 13:34:58
 
Greetings and welcome to the forums,
 
I suggest you start off with a low level of the drug and conduct a dosage escalation regimen.  
 
What is a dosage escalation regimen?
 
This is where you start with a very low dosage (say something like 0.25 mg / injection) and see how your physiology responds. Then depending upon how well you tolerated the dosage and how efficacious it was (how well it produced the desired effects) you gradually increase the dosage until such time as you find a level that you tolerate well and is efficacious for your system corresponding to your needs. You might want to wait at least two days in between injections to have a better chance for your system to fully metabolize previous injection(s) and thereby have a better chance to establish an effective dosage level for yourself.
 
-Scott
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Reply #4 - 11/10/09 at 18:03:12
 
Scott,
 
Thanks for the warm welcome and for running this site.  It is my plan to ramp up, but I plan to start at around .4mg since this seems to be the threshold that most people my age and size (172 lb) seem to see some effect.  At least from the forum.  Seems that .25 is quite low.
 
If this works as I intend, then perhaps no need to increase.  Plan to try about 1 x week, unless I can't help myself.  Trying not to put all those eggs in that basket, but I am looking for a solution that will work for my new marriage.
 
Any experience with Cagergoline?  I'd like to take to ascertain if my prolactin levels are high, since my libido and my physical response both seem "off."
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Reply #5 - 11/14/09 at 04:12:13
 
just received bremelanotide (PT-141) in mail.  4 days.  Good delivery.  Bottle in fridge now.  will reconstitute tomorrow after get syringes from pharmacy.
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Reply #6 - 11/14/09 at 22:05:42
 
syringes no problem.  Over counter.  Got 100 .5ml (50 unit).  reconstituted with 1.0 ml bac water (syringe filled twice gently into bremelanotide (PT-141)).  Took 5 units (.5mg) five minutes ago -- 5:00 pm.
 
Hoping for five hour delay and feeling like I'm 20.
 
Also taking: arginine, cialis (5mg daily), ZMA, and tongkat ali 1x day as supplements.
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Reply #7 - 11/15/09 at 00:46:07
 
Two and half hours since injection.   Facial flushing after ten minutes, lasted about an hour, then gone.  Really intense at first.  No stomach issues at all.
 
Nothing in libido dept.  Waiting.  Wife and I have "date" in about three hours.  hope batch good and I am lucky one who sees results. Wink.
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Reply #8 - 11/15/09 at 12:57:59
 
No luck.  wife super-tired so sex strained.   Shocked she trying to be good sport staying awake for romp. she knows about meds.
 
I notice nothing different during one-sided (lousy) sex, wife too tired for anything but lay there .  
 
Later, middle of night, woke with wood 2 separate times which IS different for me. .  1st around 3 am (remember I injected at 5 pm),  had hard time urinating.
 
AM on waking, slight wood at 7 am.  Nothing beyond good day.  No sexual dreams.  No feeling of youth or vigor.  Nothing I would call a libido boost.  Wouldn't call this a failure, but disappointng.  Slight effect, since unusual wood overnight.
 
Next friday will try .75mg or 1 mg to see if dose too low for 172 lbs.
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Reply #9 - 11/20/09 at 22:10:50
 
Just took 1.0mg at 4pm.  It's now 5pm.  Facial flushing as before.  Still there.  I expect for a few more minutes.  We'll see.  Hoping for more active response, and faster.
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Reply #10 - 11/21/09 at 09:36:51
 
As I mentioned in another post, I have found Vasomax with Bremelanotide to be incredibly effective (but it is expensive).  Google it an you will find a source since it is Legal in South America.  I learned of it from other sites.  It seem quite useful for those suffering from Psychogenic ED as it seems to block to some degree the erection limiting effects of stress.  Guys with "performance anxiety" have reported very good results with it.  I have taken it alone and while it was not as good as using it with bremelanotide,  I did get erections, something which never happened before with Levitra, Viagra or Cialis.  Many do use it with a small dose of Cialis or Levitra and say it is very good.
 
I have tried cabergoline, it did not seem to do much but I may have not let levels build enough.  Going to take another run at it.  Please give me you dosing regiment with Yohimbine and L arginine and the other compounds you mentioned.
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Reply #11 - 11/21/09 at 09:59:20
 
Here is a list of other things that are under investigation or have be experimented with for the treatment of ED.  The newest of the centrally acting medications is Zoraxel.  Not much is published about it but it is testing.  You can google it for an update
 
 
FDA Approved Medicines
-Cialis - Efficacy and Safety of Tadalafil for the Treatment of Erectile Dysfunction
-Levitra - Vardenafil for Treatment of Men with Erectile Dysfunction
-Viagra - High dose sildenafil citrate as a salvage therapy for severe erectile dysfunction
-Nightly PDE-5 Inhibitors - Improved spontaneous erectile function in men with mild-to-moderate arteriogenic erectile dysfunction treated with a nightly dose of sildenafil for one year
-PDE-5 Inhibitors and Vitamin E - Salvage Therapy Trial for Erectile Dysfunction Using Phosphodiesterase Type 5 Inhibitors and Vitamin E
-Injection Therapy - Intracavernous Injections of Prostaglandin E1 for Erectile Dysfunction
-MUSE - Treatment of Men with Erectile Dysfunction with Transurethral Alprostadil
-Testosterone Therapy Testosterone therapy increases sexual desire in ageing men with low–normal testosterone levels and symptoms of androgen deficiency
-Vacuum Therapy - Vacuum constriction devices for erectile dysfunction: a long-term, prospective study of patients with mild, moderate, and severe dysfunction.
 
Non-FDA Approved Medicines/Medicines Typically Used for Other Conditions
-Cozaar (Losartan) - Newest Hypertension Drugs May Improve Sexual Function
-Desyrel (Trazodone) - Trazodone for erectile dysfunction: a systematic review and meta-analysis
-Impaza - Impaza and sildenafil: comparison of clinical effectiveness in patients with erectile dysfunction
-Naltrexone - Endorphins in male impotence: Evidence for naltrexone stimulation of erectile activity in patient therapy
-Trental (Pentoxifylline) - Pentoxifylline in the treatment of erectile dysfunction due to borderline arterial insufficiency
-Uroxatral (Alfuzosin) - Effects of alfuzosin 10 mg once daily on sexual function in men treated for symptomatic benign prostatic hyperplasia
-Vasomax, Vigamed (Oral Phentolamine) - Long-term safety and efficacy of oral phentolamine mesylate (VasomaxÒ) in men with mild to moderate erectile dysfunction
-Zydena (Udenafil) - The Efficacy and Safety of Udenafil
 
Surgeries
-Implant - MECHANICAL RELIABILITY AND SAFETY OF, AND PATIENT SATISFACTION
-Revascularization - LONG-TERM FOLLOWUP AND SELECTION CRITERIA FOR PENILE REVASCULARIZATION
-Venous Ligation Surgery - Penile venous ligation surgery for the management of cavernosal venous leakage.
 
Supplements Tested on Humans
-ArginMax - The effects of ArginMax, a natural dietary supplement for enhancement of male sexual function.
-DHEA - Dehydroepiandrosterone in the treatment of erectile dysfunction
-Ginkgo Biloba - Ginkgo biloba for antidepressant-induced sexual dysfunction
-Korean Red Ginseng - Clinical efficacy of Korean red ginseng for erectile dysfunction
-L-arginine - Administration of high-dose nitric oxide donor l-arginine
-Maca - Effect of Lepidium meyenii (MACA) on sexual desire
-Pomegranate Juice - Efficacy and safety of pomegranate juice on improvement of erectile dysfunction in male patients with mild to moderate erectile dysfunction
-Prelox (Pycnogenol and L-arginine combined) - PRELOX® FOR IMPROVEMENT OF ERECTILE FUNCTION
-Pycnogenol - Lipid metabolism and erectile function improvement by pycnogenol
-Yohimbine - Effect of yohimbine hydrochloride on erectile impotence
 
Supplements Tested on Animals
-Cnidium Monnier (Osthole) - EFFECT OF THE PLANT-EXTRACT OSTHOLE ON THE RELAXATION OF RABBIT CORPUS CAVERNOSUM
-Damiana (Turnera Diffusa) - Stimulating property of Turnera diffusa and Pfaffia paniculata extracts on the sexual behavior of male rats
-Horny Goat Weed (Epimedium) - Effect of lipid-based suspension of Epimedium koreanum Nakai extract on sexual behavior in rats
-Tongkat Ali (Eurycoma Longifolia) - Effect of Eurycoma longifolia Jack on libido in middle-aged male rats
-Tribulus Terrestris - Aphrodisiac properties of Tribulus Terrestris extract (Protodioscin) in normal and castrated rats
 
Lifestyle
-Exercise - Effect of Lifestyle Changes on Erectile Dysfunction in Obese Men
-Quitting Smoking - Do cigarette smokers with erectile dysfunction benefit from stopping?
-Switching to Modified Bicycle Seats - Bicycle saddle shape affects penile blood flow
 
Psychotherapy
-Sex Therapy - The effectiveness of psychological interventions for the treatment of erectile dysfunction: systematic review and meta-analysis, including comparisons to sildenafil treatment, intracavernosal injection, and vacuum devices.
 
Non-FDA approved Medicines:
 
Cabergoline
 
-Trazodone
 
-Pentoxifylline
 
-Oral phentolamine
 
-Oxytocine
 
-Losartan
 
-Alfuzosin
 
-Impaza
 
Supplements:
 
- DHEA
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Reply #12 - 11/27/09 at 19:28:58
 
Thanks Rich for all that info.  I do want to share info with you, perhaps more depth than this in private.  
 
In the past, about 30-50mg of yohimbe has done marvels for the plumbing AND the wiring for me.  I also take at least 3000mg l'arginine  at at time, and that seems to help other supplements or meds work better.  Without the Cialis only Yohimbe has been 100% reliable.  It keeps me awake for the entire night, something I am willing to do but would rather not.  I have abstained for about a month from that and am trying bremelanotide (PT-141) instead.  Actually am considering trying melanotan II as it also takes care of Rosacea as well, something I have to a small degree on my face.  I have also been taking LJ100 (tongkat ali) in varying doses to experiment with increased testosterone or libido effects.  So far, nothing conclusive.  I am afraid with supplements I need to be more systematic.  I seem to be more desperate at this stage, which supersedes my scientific method.
 
Anyhow, last time I took 1.0 mg bremelanotide (PT-141), and around 5.5 hours after injection I got a small effect of increased libido that would best be termed by me as a "matter of fact" attitude about my sex.  Significantly better than the usual doubt..is it going to work this time?  
 
Wife and I went on for about 45 minutes, many different positions, and I never had a doubt about whether I would keep wood or not.  Actually at one point lost breath and wood, but it returned after a minute.  I was a little disappointed as I didn't get the effect many on this forum report that horny- devilish feeling of a 17-year-old libido, but it did have a positive effect.
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Reply #13 - 11/27/09 at 19:40:33
 
So.  I just injected with bremelanotide (PT-141) at 1.3mg about 25 minutes ago.  Facial flushing.  Am trying earlier in the day (2pm) to see if I can get more "use."
 
Also taking 3500 mg L'arginine, and 200 mg Tongkat Ali.
 
I always eat 1000 mg epimedium (HGW) about an hour or two before "date".
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