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Tanning cream may ward off skin cancer (Read 17820 times)
petee677
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Tanning cream may ward off skin cancer
09/20/06 at 22:13:10
 
Saw this interesting news article:
 
http://news.yahoo.com/s/nm/20060920/sc_nm/tanning_cancer_dc
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« Last Edit: 09/21/06 at 00:14:55 by petee677 »  
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GiveMeATan
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Re: Tanning cream may ward off skin cancer
Reply #1 - 09/21/06 at 00:46:49
 
Even greater than melanotan, ecspecially if it doesn't cause freckling/agespots/moles darkening etc.
Then again, melanotan was discovered like 15 years ago... so... this won't be out before 2015 or so;\
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Re: Tanning cream may ward off skin cancer
Reply #2 - 09/21/06 at 01:22:44
 
Without knowing anything about it at all, I suspect it could cause exactly the same freckling problems people have experienced with melanotan-1 and melanotan II.
 
My gut feeling is that if you have areas that are susceptible to hyperpigmentation, then a tan of any sort (regardless of what tanning agent caused it) may exaggerate this - creating freckles. Maybe these people have always had these spots of hyperpigmentation, but without any major pigmentation to "colour them in" the spots remain invisible. ???
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Re: Tanning cream may ward off skin cancer
Reply #3 - 09/21/06 at 02:56:50
 
Does anyone believe that this may be similar to Dr. Fuller's MelanX ??
 
Whatever happened to that......
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Re: Tanning cream may ward off skin cancer
Reply #4 - 09/21/06 at 03:45:21
 
Nature is one the most highly respected scientific Journals, so it is pretty exciting to see this published.  Forskolin is widely available..
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Re: Tanning cream may ward off skin cancer
Reply #5 - 09/21/06 at 06:02:19
 
Wow, it looks like Forskolin is a wonder drug!  It has a lot of good effects on the body, from halting cancer growth to losing weight and building muscle to tanning!
 
However, the topical Forskolin is touted to burn local fat (cellulite) but there is no mention of a tanning effect.  How could this be?  Surely anyone using topical forskolin should see the skin tan as a "side effect".  It seems to be a contradiction.  Does anyone know the answer?  Is there a Forskolin Forum somewhere?
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GiveMeATan
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Re: Tanning cream may ward off skin cancer
Reply #6 - 09/21/06 at 13:00:01
 
Hopefully someone who knows something about this drug can tell us more =)
This would seriously kill melanotan peptides tan/sunprotection market, I'd rather use a cream than a injection, no doubt most of the world would too.
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Re: Tanning cream may ward off skin cancer
Reply #7 - 09/21/06 at 19:37:27
 
this sounds promising id like to know more we should keep this issue alive. are u saying this is available already but is used for fat/cellulite or whatever but it doesnt say anything about tanning.maybe a stronger concentration is needed for tanning purposes.
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Re: Tanning cream may ward off skin cancer
Reply #8 - 09/21/06 at 20:10:27
 
Hi,
 
Having done a quick review of various scientific papers, it appears that Forskolin has been linked to the tanning process by a number of sources. However, one potential problem is that the commonly available Forskolin compound might not be formulated to penetrate human skin deeply enough to activate the tanning cells. The study in Nature was based on rats who have much thinner skin. This may explain why people already using Forskolin for other purposes have not complained of dark patches appearing on their skin. I'm only guessing with all of this though, I'm no expert. If I am wrong and Forskolin will penetrate sufficiently or if there is a way to increase it's penetration with one of the compounds already mentioned on other strands of this forum, we might have a serious and possibly superior alternative to melanotan II. Any big brains out there have any comment or futher thoughts?
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Re: Tanning cream may ward off skin cancer
Reply #9 - 09/21/06 at 23:37:10
 
It sounds promising - I will be interested to see future studies into it. Epitan was talking years ago about making melanotan-1 a cream based topical, although I don't know where they got to in the research and whether the new direction of the company is allowing for that kind of research.  Still, being able to apply melanotan-1 and melanotan II as a topical would certainly be much more user-friendly.
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Re: Tanning cream may ward off skin cancer
Reply #10 - 09/21/06 at 23:44:09
 
Forskolin?? Sorry guys I'm a bit lost.  I read the article on the link and I don't see anything about Forskolin????
 
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Re: Tanning cream may ward off skin cancer
Reply #11 - 09/22/06 at 00:05:05
 
Just do a google search, remeber Forskolin, not Foreskin! lol
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petee677
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Re: Tanning cream may ward off skin cancer
Reply #12 - 09/22/06 at 02:49:14
 
I have to say that I still like the idea of melanotan vs. a topical cream just for the simple fact that melanotan is systemic. However, the HUGE benefit that this cream would have is that it produces a tan without sun exposure. According to Epitan/Clinuvel, melanotan is supposed to do this, but I think we've debunked this myth through the informative posts people have made on this forum regarding their experimentation with melanotan and melanotan II.  
 
Anyway, a cream like this may have similar drawbacks to self-tanners in that it could be applied unevenly causing streaks, spots, etc., but in the end I think the sunless aspect of it overpowers the drawbacks.
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Re: Tanning cream may ward off skin cancer
Reply #13 - 09/22/06 at 06:57:54
 
I doubt that this cream can give a good tan without the sun.  In their trials with the mice, all the mice were subjected to so much UV that they all died of skin cancer!  Check it out at:
 
www.nature.com/news/2006/060918/full/060918-6.html
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Re: Tanning cream may ward off skin cancer
Reply #14 - 09/22/06 at 08:10:10
 
I think that perhaps you may have read that particular sentence about the death of the mice the wrong way - my reading of it is that the ones that were untreated died, and although the half of the mice that had the forskolin did develop tumours from high level radiation, it took much longer and it doesnt say they died.    
 
I might be reading it the wrong way myself though Smiley
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Re: Tanning cream may ward off skin cancer
Reply #15 - 09/22/06 at 15:13:05
 
They did expose the mice to UV rays, but it looks like they did so to test the effectiveness of the treatment. They had the one group of mice that had been genetically engineered to burn like crazy and the other group that had been treated with forskolin prior to UV exposure. I think what they did is just push it to the limits with the UV exposure for the purpose of testing it.  
 
The article also states that only half of the treated mice developed tumors and that was after 50 weeks of exposure, compared to the untreated mice that all died after only 30 weeks. As Emma said, the article doesn't mention whether the treated mice died from the tumors at that point.
 
Here are a couple of quotes from the two articles that make me think this works without UV exposure:
 
"Scientists say they have discovered a cream that may ward off skin cancer by tanning skin a golden bronze without exposure to the sun."
 
"Researchers have found a chemical from a tropical mint plant that works both as a sunless tanner and as a solar shield..."
 
"Unlike other sunless tanners on the market that simply dye the skin, forskolin prompts the body to produce a real tan, protecting against ultraviolet radiation."
 
I'll admit that I haven't read the actual study yet, but if it could work without UV exposure, this stuff would be amazing!
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Re: Tanning cream may ward off skin cancer
Reply #16 - 09/22/06 at 15:29:04
 
I'm going to grow a "Coleus plant" garden now!!!!!    jk!
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Re: Tanning cream may ward off skin cancer
Reply #17 - 09/23/06 at 00:21:55
 
I still rather use melanotan II ..one shot takes a couple of minutes.
 
With the cream u would have to cover entire body which is a pain in the arse.  
 
Ask the people who use the sunless tanners how much of a pain that was to do all the time.
 
We still don't know (Being that it's still being tested) if we would have to apply it everyday or what.  Also ,what if we missed some spots would we have streaks of tan?
 
Or do we jusy have to aplly it to one area and ir works the entire body?
 
Who knows..sounds interesting but allot of questions .
 
Blue
 
PS:Anyway I'm going to look into this plant myself .
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Re: Tanning cream may ward off skin cancer
Reply #18 - 09/23/06 at 00:34:09
 
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Re: Tanning cream may ward off skin cancer
Reply #19 - 09/23/06 at 00:34:50
 
I wonder if it would work if we took it as a supplement as oppose to a topical treatment?
 
Blue
 
http://www.raysahelian.com/coleusforskohlii.html
 
Coleus Forskohlii by Ray Sahelian, M.D.
 
Coleus forskohlii is an important traditional Ayurvedic herb that has been a part of Indian medicine for centuries. In the 1970s, researchers isolated a chemically active extract from coleus forskohlii and called it forskolin. Now available in supplement form, coleus forskohlii extract has been tested in a number of conditions.  
 
Coleus Forskohlii Extract, 60 Capsules - Enzymatic Therapy
 
 
Coleus Forskohlii extract is produced from the root of Coleus forskohlii, an ancient Ayurvedic plant. Coleus forskohlii is the source of a unique substance known as forskolin.  Modern extraction and analytical techniques are used to produce the highest quality extract available. Each batch of Coleus Forskohlii extract is analyzed and guaranteed to contain a minimum of 18% forskolin.
 
 
 
Coleus Forskohlii Supplement Facts
Serving Size 1 capsule
 
Coleus Forskohlii root extract - 50 mg*
      Standardized to contain 18%
      Forskolin (9 mg per capsule)
 
* Coleus Forskohlii daily values not establishe
 
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