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topical forskolin (Read 3117 times)
jdawson
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topical forskolin
11/29/06 at 20:03:08
 
has anyone seen any convincing results from their topical forskolin trials. If so, what delivery system/regimen ru using?
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WiseGuy
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Re: topical forskolin
Reply #1 - 11/29/06 at 20:32:35
 
I dont think so yet, but i could be wrong i know SocialGuy has been testing it you should check out his thread.
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Re: topical forskolin
Reply #2 - 05/23/12 at 10:16:00
 
I would have thought that forskolin would be a non-issue since the melanocortins arrived.
Yes, I've been fooling around with forskolin for awhile and did indeed induce a tan.
I only applied it once a week for two weeks and didn't bother to shade the rest of my skin in the area, but it clearly works.
I need to improve the method, however it shows that the mice that tanned in the study have nothing on us humans.
If anyone is interested I can post a picture.
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Re: topical forskolin
Reply #3 - 05/23/12 at 16:14:34
 
Please do!
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Nyles7
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Re: topical forskolin
Reply #4 - 05/23/12 at 22:07:45
 
Here is a picture of the forskolin treated forearm area (on right) vs the normal tanned area (left) from just wearing short sleeves outside. I hope the contrast shows up. If people are interested I could try the stuff on a less sun exposed area to possibly better highlight the forskolin treated area.
It should be noted that I used 98% forskolin, which is a light colored powder and not the lower 10% or 20% which has residual dark pigments from the plant, so this darkened area is not an artifact caused by the less pure extract.  What you see is the result of two applications, one week apart though it was noticeable after the first application.
(Ignore the minor wound on the lower left and my manly hairs  Smiley)
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Re: topical forskolin
Reply #5 - 05/23/12 at 22:50:45
 
Hi,
 
What medium/liquid did you use to apply the forskolin powder?
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Re: topical forskolin
Reply #6 - 05/24/12 at 09:53:08
 
Thanks for sharing the photo! I'm also interested in how you applied the powder. Also, how did you source the 98% forskolin? Directly from a lab?
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Nyles7
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Re: topical forskolin
Reply #7 - 05/24/12 at 20:33:53
 
Thanks.
The carrier of the forskolin is pretty unglamorous.
Let me get another analog of this carrier, test it, and then I reveal it.
The picture that I posted is pretty poor.  
The tan looks about equal with the far left side of the picture, which it is not.  
I think it's simply a shadow on the left. I'll try applying it on a shaded area that lacks any tan and then I'll repost. Ideally my girlfriend, a redhead that can't tan, would try it, but she's not a fan of self-experimentation, no matter how benign.
Sabina offers high purity forskolin. That's where mine comes from.
I had used it in developing a topical anti-inflammatory for seborrhea and eczema, which is actually phenomenal when forskolin is mixed with a xanthine derivative. Even seems to nearly stop poison ivy dermatitis if used after exposure. I suppose that's for another forum. Anyway, I had some extra forskolin from that experiment that I was playing with.
So yes forskolin works molecularly on humans as it did for mice in the D'Orazio (et al) and Spry (et al) papers. Maybe it should be tried with both forskolin and procyanidins for hair growth, as in the 2000 Takahasi (et al) paper.
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Re: topical forskolin
Reply #8 - 05/24/12 at 21:13:46
 
Nyles7:
 
We would be most grateful if you would follow through with your news of the carrier and if possible, some clearer photos from your second trial.
 
Best wishes
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Re: topical forskolin
Reply #9 - 05/25/12 at 12:59:33
 
Thanks for the info! Fascinating stuff, please keep us posted. I'm very interested in this.
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Re: topical forskolin
Reply #10 - 05/26/12 at 01:04:02
 
I know forskolin could also increase hair pigmentation and was also used in an eyelash serum named talika lipocils ( to grow in darker lashes for light haired and redheads) . Could the mix for skin be used on your head of should I add something to make it work specifically for hair follicles?  
I've been experimenting with the 20 pct version and had two hairs growing in darker ( never ever had a dark hair on my body before) but as I'm not a scientist and just used a bodymilk and some ethanol, it's probably not the best method to achieve my goals.
 
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« Last Edit: 05/26/12 at 09:52:54 by Beebeep »  
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Re: topical forskolin
Reply #11 - 06/16/12 at 09:41:53
 
Any updates?
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Nyles7
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Re: topical forskolin
Reply #12 - 06/16/12 at 09:54:18
 
In fact, yes.
I've been using it on the untanned crease of my inner arm.
This area sees little sun because I usually wear long sleeves and live in Hell...I mean near Olympia Washington, which gets little sun.
It is tanning, but it's sort of blotchy, lighter, and took much longer than areas of the body that regularly exhibit a tan.
I'm wondering if this is because the inner crease of the arm simply is not conducive to easy tanning (UV or otherwise) or it's possible that the sun's UV augments the forskolin induction of a tan.
I suspect it's the former, but who knows?
I'll post a picture in the next day or so.
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Re: topical forskolin
Reply #13 - 06/16/12 at 17:38:40
 
Cool, thanks for updating the thread.
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Re: topical forskolin
Reply #14 - 06/17/12 at 22:13:25
 
Thank you for the update, your news is most welcome.  
 
I hope you will be able to share your carrier method and what type/percentage of Forskolin extract you are using?
 
BW
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Re: topical forskolin
Reply #15 - 06/17/12 at 22:45:18
 
Quote from darkhorse on 06/17/12 at 22:13:25:

I hope you will be able to share your carrier method and what type/percentage of Forskolin extract you are using?

I hope so as welll Smiley Any details are appreciated.
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Nyles7
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Re: topical forskolin
Reply #16 - 06/18/12 at 00:17:09
 
Here is the picture I promised of "Round II" of the forskolin tanning experiment.
It's the inside of my arm which doesn't get a lot of sun and even less so because I am in Olympia Washington (which is indeed Hell on Earth).
I am using 98% forskolin purchased from Sabinsa which is essentially a white extract, unlike the lower purity forskolin extracts that have a lot of dark plant pigments remaining and might confound the test results by staining the skin.
 
The left side of my arm in the picture is untreated (the control) and the right side, in and around the arm crease, is treated (maybe 4 doses?). Both sides of the arm should have gotten about the same ambient sun exposure.
 
You're saying to yourself "It sort of looks like dirt"
Not so much dirt in reality, as it's an uneven tan.
(there are a few small moles which seem to have gotten darker and can also be seen)
But yes, even I must admit that it does indeed look like dirt in the picture, which I'm hoping will make the picture more compelling since anyone faking positive results would hardly choose to post a forskolin tan that looks like this   Smiley
 
Nonetheless, there is something real going on.
 
I don't want to give out my method, not that I'm going to market it, but I think there are better ones out there and I don't want to contaminate your ideas. If you want to play with this (and I hope you do), you might want to pick up some Dr Bronner's Peppermint Pure Castile Soap (liquid) and exfoliate the skin prior to applying (hint).
Forskolin is NOT soluble in this soap, but the soap is a great transdermal carrier.
You shouldn't need a very pure forskolin extract, however don't let any skin staining by the very heavily pigmented lower concentrations of forskolin fool you into thinking you've tanned!
 
Remember what Richard Feynman said..."The first principle is that you must not fool yourself and you are the easiest person to fool."
 
I'd appreciate if any further experimenters would continue posting to this thread so I can find the subsequent posts.
 
Don't do anything to animals that you wouldn't try on yourself if you were in their situation.
 
Good luck and keep me up to date!
 
Nyles
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« Last Edit: 06/18/12 at 00:43:43 by Nyles7 »  

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Re: topical forskolin
Reply #17 - 06/18/12 at 16:10:37
 
thank for the Dr Bronner's Peppermint Pure Castile Soap, I'm also experimenting with forskolin and I'm looking out to use it for hair darkening as well. So far a couple of darker hairs have started to grow in. But I think it's all about finding the right penetration and concentration. So I might order the castile soap. Would it make a major difference?
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Re: topical forskolin
Reply #18 - 06/18/12 at 22:21:42
 
I have no idea why this soap in particular is so effective as a transdermal vehicle. Maybe some of the other Castile soaps are also as good, but I seem to always have the best luck with this one.
So in answer to your question, yes I would order this one by name.  
It's the liquid soap in the plastic bottle.  
It is not the solid bar of soap.
A little goes a long way, so just order the small bottle unless you're going to also use it for its intended purpose. It's good stuff in either case.
 
Keep me posted!
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Re: topical forskolin
Reply #19 - 09/29/12 at 17:05:06
 
Nyles7,  
 
Did you ever get any furthe with your experiements?
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