Socalguy
-Melanotanner-
  

Got Melanotan.org?
Posts: 478
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My post #67 outlined my plan with sun exposure to the test areas. Since the sun is now in the southern hemisphere and getting weak here I tried to get exposure around noon. 11-10 20min. uv, 11-11 cloudy no uv, 11-12 30mins., 11-13 & 14 45mins., 11-15 & 16 50 mins. The photo 2 days since I last applied forskolin and took last UV shows: I only got sunburned on the exposed skin and broke out with a PMLE reaction. So the forskolin did not protect my skin nor produce any significant darkening. It's interesting that the lowest patch #1 untreated skin with no sunscreen, shows less sunburn than patches # 2,3,4 the treated skin. This leads me to believe that Forskolin may be a photosensitizer just like the Psoralens. I will take another photo in two days, hopefully the PMLE will have decreased and sunburn gone away enough to see if there is any darkening. Since I never had a tan or used melanotan/melanotan II, I can't say if or how dark I could get. Human skin is thicker than mice. 1] I believe the propylene glycol is not an adequate transporter of the forskolin through the human skin. 2] I believe for the forskolin to work, it would need to be put into a liposome form to penetrate down to the dermis. I tried adding it to some liposome creams I had, but this did nothing not even stain the skin. 3] I think it needs to be chemically engineered into a liposome form by a chemical lab who specialize in this. Maybe Dr. Fisher's Co. will be able to develope this and hopefully the FDA won't have to get involved. One person does not make a conclusive trial. Perhaps other type I & II's will try and report their results in detail. It may work in others. Even the cautious FDA approves all sorts of drugs that show results in only 50-60% of tests. Those of you who can't get 98% ethanol, I found that 99% Isopropyl alcohol did take the forskolin into solution. I bought it off the shelf at Vons market- Safeway brand $2.00/pint. you can buy propylene glycol at a compounding pharmacy. I may try a short trial using DMSO, a local herb store has it $13.50/8oz.
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