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Soclguy's trial with C. Forskolin (Read 47495 times)
Socalguy
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Re: Soclguy's trial with C. Forskolin
Reply #100 - 12/11/06 at 17:00:18
 
Thanks KaKarot,
Yes after I had this reaction, I found that Dr. Stanley Jacobs
" The father of DMSO" ecommends 70%. It nevertheless scared me sufficiently to be very cautious.
DMSO Penetrates Membranes and Eases Pain
 
The first quality that struck Dr. Jacob about the drug was its ability to pass through membranes, an ability that has been verified by numerous subsequent researchers.1 DMSO's ability to do this varies proportionally with its strength--up to a 90 percent solution. From 70 percent to 90 percent has been found to be the most effective strength across the skin, and, oddly, performance drops with concentrations higher than 90 percent. Lower concentrations are sufficient to cross other membranes. Thus, 15 percent DMSO will easily penetrate the bladder.2  
 
In addition, DMSO can carry other drugs with it across membranes. It is more successful ferrying some drugs, such as morphine sulfate, penicillin, steroids, and cortisone, than others, such as insulin. What it will carry depends on the molecular weight, shape, and electrochemistry of the molecules. This property would enable DMSO to act as a new drug delivery system that would lower the risk of infection occurring whenever skin is penetrated.  
 
DMSO perhaps has been used most widely as a topical analgesic, in a 70 percent DMSO, 30 percent water solution. Laboratory studies suggest that DMSO cuts pain by blocking peripheral nerve C fibers.3 Several clinical trials have demonstrated its effectiveness,4,5 although in one trial, no benefit was found.6 Burns, cuts, and sprains have been treated with DMSO. Relief is reported to be almost immediate, lasting up to 6 hours. A number of sports teams and Olympic athletes have used DMSO, although some have since moved on to other treatment modalities. When administration ceases, so do the effects of the drug.  
 
Dr. Jacob said at a hearing of the U.S. Senate Subcommittee on Health in 1980, "DMSO is one of the few agents in which effectiveness can be demonstrated before the eyes of the observers....If we have patients appear before the Committee with edematous sprained ankles, the application of DMSO would be followed by objective diminution of swelling within an hour. No other therapeutic modality will do this."  
 
Chronic pain patients often have to apply the substance for 6 weeks before a change occurs, but many report relief to a degree they had not been able to obtain from any other source.  
 
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Re: Soclguy's trial with C. Forskolin
Reply #101 - 01/06/07 at 23:17:37
 
Soclguy, can you update on your Forskolin experiment and what you are doing now?
 
I've recently read that in many experiments both DMSO and propylene gycol can induce slight melanogenesis on their own entirely.  
 
I would use a mix of 3:1 prop gycol to DMSO as vehicle for Forskolin and most other things too.
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Re: Soclguy's trial with C. Forskolin
Reply #102 - 01/07/07 at 03:30:20
 
KK,
I have ended the Forskolin trial.
I have been doing the DNA repair cream, Melanobronze,and recently melanotan II combined with them. I wanted to give all enough time, so as not to raise false hopes with any premature reports. The holidays and other things have not given me enough time to write up a complete report, but I will soon, My apologies. I have reported on your other thread about the DNA repair lotion.
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Re: Soclguy's trial with C. Forskolin
Reply #103 - 01/07/07 at 04:30:24
 
You're using melanotan II with Melanobronze?  How you gonna validate Melanobronze if you do that?
 
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Re: Soclguy's trial with C. Forskolin
Reply #104 - 01/07/07 at 04:30:51
 
And the DNA repair cream doesn't tan you does it?
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Re: Soclguy's trial with C. Forskolin
Reply #105 - 01/08/07 at 02:27:35
 
Kakarot,
Read my new thread on Melanobronze & melanotan II and you will understand my rational.
 
The DNA repair lotion is not to tan you but to repair prior skin damage that has occured from sun exposure in our lives.
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Re: Soclguy's trial with C. Forskolin
Reply #106 - 01/08/07 at 04:23:36
 
Quote from Socalguy   on 01/08/07 at 02:27:35:
Kakarot,
Read my new thread on Melanobronze & melanotan II and you will understand my rational.

The DNA repair lotion is not to tan you but to repair prior skin damage that has occured from sun exposure in our lives.

 
Are you still tanned from the Forskolin?
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Re: Soclguy's trial with C. Forskolin
Reply #107 - 01/08/07 at 22:44:55
 
Quote from melanotan IIisCool_   on 01/08/07 at 04:23:36:


Are you still tanned from the Forskolin?

 
I ended the Forskolin long ago- so no.
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Re: Soclguy's trial with C. Forskolin
Reply #108 - 06/24/10 at 12:01:19
 
I THINK the key is to combine the extract with something that can penetrate the skin and or hair follicles. I have heard aloe vera is a good penetrator, I have heard horror stories about dmso, but maybe it's brand or dose depending
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